Ontology highlight
ABSTRACT:
SUBMITTER: Singh M
PROVIDER: S-EPMC6648008 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Singh Mala M Singh Anoop S AS Mishra Nidhi N Agrahari Anand K AK Tiwari Vinod K VK
ACS omega 20190131 1
Benzotriazole has been established as an efficient ligand in Cu-catalyzed cross-coupling of terminal alkynes to form 1,3-dialkynes using CuI as the catalyst and K<sub>2</sub>CO<sub>3</sub> as the base at room temperature in an open round-bottom flask. The established protocol has the following notable advantages: simple to handle, easy work-up, mild reaction condition, high substrate scope, requirement of less quantity of ligand and also Cu-catalyst, less expensive, and high reaction yield. ...[more]