Ontology highlight
ABSTRACT:
SUBMITTER: Petralia MC
PROVIDER: S-EPMC6651482 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Petralia Maria Cristina MC Mazzon Emanuela E Fagone Paolo P Russo Andrea A Longo Antonio A Avitabile Teresio T Nicoletti Ferdinando F Reibaldi Michele M Basile Maria Sofia MS
Molecules (Basel, Switzerland) 20190704 13
Uveal melanoma (UM) represents the most frequent primary intraocular tumor, however, limited therapeutic options are still available. We have previously shown that cluster of differentiation 47 (CD47) is significantly upregulated in UM cells following inflammatory stimuli and that it represents a predictor of disease progression. Here, we aimed to better characterize the pathophysiological role of CD47 in UM. We show that CD47 is not modulated at different cancer stages, although patients with t ...[more]