Ontology highlight
ABSTRACT:
SUBMITTER: Onder Y
PROVIDER: S-EPMC6664146 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Onder Yasemin Y Laothamatas Isara I Berto Stefano S Sewart Katharina K Kilaru Gokhul G Bordieanu Bogdan B Stubblefield Jeremy J JJ Konopka Genevieve G Mishra Prashant P Green Carla B CB
iScience 20190716
Fine-tuning of transcriptional responses can be critical for long-term outcomes in response to an environmental challenge. The circadian protein Nocturnin belongs to a family of proteins that include exonucleases, endonucleases, and phosphatases and is most closely related to the CCR4 family of deadenylases that regulate the cellular transcriptome via control of poly(A) tail length of RNA transcripts. In this study, we investigate the role of Nocturnin in regulating the transcriptional response ...[more]