Ontology highlight
ABSTRACT:
SUBMITTER: Salnikov OG
PROVIDER: S-EPMC6664436 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
The journal of physical chemistry. C, Nanomaterials and interfaces 20190419 20
<sup>13</sup>C-hyperpolarized carboxylates, such as pyruvate and acetate, are emerging molecular contrast agents for MRI visualization of various diseases, including cancer. Here we present a systematic study of <sup>1</sup>H and <sup>13</sup>C parahydrogen-induced polarization of acetate and pyruvate esters with ethyl, propyl and allyl alcoholic moieties. It was found that allyl pyruvate is the most efficiently hyperpolarized compound from those under study, yielding 21% and 5.4% polarization o ...[more]