Ontology highlight
ABSTRACT:
SUBMITTER: Udhwani T
PROVIDER: S-EPMC6677907 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Udhwani Trishang T Mukherjee Sourav S Sharma Khushboo K Sweta Jajoriya J Khandekar Natasha N Nayarisseri Anuraj A Singh Sanjeev Kumar SK
Bioinformation 20190228 2
The progression of lung cancer is associated with inactivation of programmed cell death protein 1, abbreviated as PD- 1 which regulates the suppression of the body's immune system by suppressing T- cell inflammatory activity and is responsible for preventing cancer cell growth. It is of interest to identify inhibitors for PD-L1 dimeric structure through molecular docking and virtual screening. The virtual screened compound XGIQBUNWFCCMAS-UHFFFAOYSA-N (PubChem CID: 127263272) displays a high affi ...[more]