Ontology highlight
ABSTRACT:
SUBMITTER: Kouznetsova A
PROVIDER: S-EPMC6680117 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Kouznetsova Anna A Kitajima Tomoya S TS Brismar Hjalmar H Höög Christer C
EMBO reports 20190710 8
The accuracy of the two sequential meiotic divisions in oocytes is essential for creating a haploid gamete with a normal chromosomal content. Here, we have analysed the 3D dynamics of chromosomes during the second meiotic division in live mouse oocytes. We find that chromosomes form stable kinetochore-microtubule attachments at the end of prometaphase II stage that are retained until anaphase II onset. Remarkably, we observe that more than 20% of the kinetochore-microtubule attachments at the me ...[more]