Ontology highlight
ABSTRACT:
SUBMITTER: Dong Y
PROVIDER: S-EPMC6681348 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Dong Yanjing Y Shi Daning D Ying Yuan Y Xi Xinping X Chen Xiaoling X Wang Lei L Zhou Mei M Wu Qinan Q Ma Chengbang C Chen Tianbao T
Biomolecules 20190628 7
Protease inhibitors that were identified from amphibian skin secretions with low molecular weights and potent inhibitory activity were thought to be potential candidates for novel peptide drugs. Here, a novel peptide with trypsin inhibitory activity was found in the skin secretion of the Chinese bamboo leaf odorous frog, <i>Odorrana versabilis</i>. Based on the sequence alignments of sequencing results, the novel peptide (ALKYPFRCKAAFC) was named as Kunitzin-OV. The synthetic replicate of Kunitz ...[more]