Ontology highlight
ABSTRACT:
SUBMITTER: Sonawane SK
PROVIDER: S-EPMC6682074 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Sonawane Shweta Kishor SK Ahmad Absar A Chinnathambi Subashchandrabose S
ACS omega 20190729 7
The Alzheimer's disease (AD) therapeutic research is yielding a large number of potent molecules. The nanoparticle-based therapeutics against the protein aggregation in AD is also taking a lead especially with amyloid-β as a primary target. In this work, we have screened for the first time protein-capped (PC) metal nanoparticles for their potency in inhibiting Tau aggregation in vitro. We present a novel function of PC-Fe<sub>3</sub>O<sub>4</sub> and PC-CdS nanoparticles as potent Tau aggregatio ...[more]