Ontology highlight
ABSTRACT:
SUBMITTER: Cong J
PROVIDER: S-EPMC6685025 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Cong Jing J Fang Bing B Wang Qian Q Su Yan Y Gu Tianqi T Luo Tianzhi T
Journal of the Royal Society, Interface 20190724 156
Myosin II and spectrin β display mechanosensitive accumulations in invasive protrusions during cell-cell fusion of Drosophila myoblasts. The biochemical inhibition and deactivation of these proteins results in significant fusion defects. Yet, a quantitative understanding of how the protrusion geometry and fusion process are linked to these proteins is still lacking. Here we present a quantitative model to interpret the dependence of the protrusion size and the protrusive force on the mechanical ...[more]