A non-intrusive evaluation method for tumor-targeting characteristics of nanomedicines based on in vivo near-infrared fluorescence imaging.
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ABSTRACT:
SUBMITTER: Liu H
PROVIDER: S-EPMC6686867 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Publications
A non-intrusive evaluation method for tumor-targeting characteristics of nanomedicines based on in vivo near-infrared fluorescence imaging.
Liu Hao H Marquez Rebecca T RT Wu Xiaoqing X Li Ke K Vadlamani Shweta S Li Song S Wang Ya Y Xu Liang L Wu Daocheng D
Journal of materials chemistry. B 20190801 31
We developed a novel evaluation method for tumor-targeting characteristics of nanomedicines, average tumor-targeting index (average TTI) and "area under the tumor-targeting index-time curve" (AUTC) were established as the indicators for tumor targeting of nanomedicines based on NIR fluorescence imaging, which helps real-time monitoring of targeting ability and tumor changes in vivo without culling animals. ...[more]
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