Ontology highlight
ABSTRACT:
SUBMITTER: Kalmykov A
PROVIDER: S-EPMC6707782 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Kalmykov Anna A Huang Changjin C Bliley Jacqueline J Shiwarski Daniel D Tashman Joshua J Abdullah Arif A Rastogi Sahil K SK Shukla Shivani S Shukla Shivani S Mataev Elnatan E Feinberg Adam W AW Hsia K Jimmy KJ Hsia K Jimmy KJ Cohen-Karni Tzahi T
Science advances 20190823 8
Cell-cell communication plays a pivotal role in coordination and function of biological systems. Three-dimensional (3D) spheroids provide venues to explore cellular communication for tissue development and drug discovery, as their 3D architecture mimics native in vivo microenvironments. Cellular electrophysiology is a prevalent signaling paradigm for studying electroactive cells. Currently, electrophysiological studies do not provide direct, multisite, simultaneous investigation of tissues in 3D ...[more]