Ontology highlight
ABSTRACT:
SUBMITTER: Lange H
PROVIDER: S-EPMC6711988 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Lange Heike H Ndecky Simon Y A SYA Gomez-Diaz Carlos C Pflieger David D Butel Nicolas N Zumsteg Julie J Kuhn Lauriane L Piermaria Christina C Chicher Johana J Christie Michael M Karaaslan Ezgi S ES Lang Patricia L M PLM Weigel Detlef D Vaucheret Hervé H Hammann Philippe P Gagliardi Dominique D
Nature communications 20190827 1
The RNA exosome is a key 3'-5' exoribonuclease with an evolutionarily conserved structure and function. Its cytosolic functions require the co-factors SKI7 and the Ski complex. Here we demonstrate by co-purification experiments that the ARM-repeat protein RESURRECTION1 (RST1) and RST1 INTERACTING PROTEIN (RIPR) connect the cytosolic Arabidopsis RNA exosome to the Ski complex. rst1 and ripr mutants accumulate RNA quality control siRNAs (rqc-siRNAs) produced by the post-transcriptional gene silenc ...[more]