Ontology highlight
ABSTRACT:
SUBMITTER: Wei L
PROVIDER: S-EPMC6733574 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Wei Lu L Al Oustah Amir A Blader Patrick P Roussigné Myriam M
eLife 20190909
Coordinated migration of cell collectives is important during embryonic development and relies on cells integrating multiple mechanical and chemical cues. Recently, we described that focal activation of the FGF pathway promotes the migration of the parapineal in the zebrafish epithalamus. How FGF activity is restricted to leading cells in this system is, however, unclear. Here, we address the role of Notch signaling in modulating FGF activity within the parapineal. While Notch loss-of-function r ...[more]