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Complete Genome Sequence of Herpes Simplex Virus 1 Strain MacIntyre.

ABSTRACT: Herpes simplex virus type 1 (HSV-1) strain MacIntyre has a severe defect in the anterograde spread after replication in the nucleus. To better understand and identify the genetic determinants that lead to the unique phenotypes of the MacIntyre strain, we sequenced its genome with PacBio single-molecule real-time sequencing technology and resolved the complete sequence.

SUBMITTER: Jiao X

PROVIDER: S-EPMC6742799 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

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Complete Genome Sequence of Herpes Simplex Virus 1 Strain MacIntyre.

Jiao Xiaoli X Sui Hongyan H Lyons Christopher C Tran Bao B Sherman Brad T BT Imamichi Tomozumi T

Microbiology resource announcements 20190912 37

Herpes simplex virus type 1 (HSV-1) strain MacIntyre has a severe defect in the anterograde spread after replication in the nucleus. To better understand and identify the genetic determinants that lead to the unique phenotypes of the MacIntyre strain, we sequenced its genome with PacBio single-molecule real-time sequencing technology and resolved the complete sequence. ...[more]

PMID: 31515348

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