Ontology highlight
ABSTRACT:
SUBMITTER: Glickstein SB
PROVIDER: S-EPMC6758242 | biostudies-literature | 2002 Jul
REPOSITORIES: biostudies-literature
Glickstein Sara B SB Hof Patrick R PR Schmauss Claudia C
The Journal of neuroscience : the official journal of the Society for Neuroscience 20020701 13
Mice deficient for dopamine D(2) and D(3) receptors exhibit blunted c-fos responses to D(1) agonist stimulation. Stereologic cell counting revealed decreased numbers of medial prefrontal cortex neurons that express Fos immunoreactivity in all layers, particularly in the prelimbic and anterior cingulate subregions. Pretreatment of these mutants with a single, low dose of methamphetamine (METH) led to a sustained increase in the number of neurons that express Fos immunoreactivity in response to a ...[more]