Ontology highlight
ABSTRACT:
SUBMITTER: Spaltenstein P
PROVIDER: S-EPMC6767911 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Spaltenstein Paul P Cummins Elizabeth J EJ Yokuda Kelly-Marie KM Kowalczyk Tim T Clark Timothy B TB O'Neil Gregory W GW
The Journal of organic chemistry 20190313 7
Alkoxyallylsiletanes are capable of highly chemo- and diastereoselective carbonyl allylsilylations. Reactive substrates include salicylaldehydes and glyoxylic acids. Chemoselectivity in these reactions is thought to arise from a mechanism involving first exchange of the alkyoxy group on silicon with a substrate hydroxyl followed by activation of a nearby carbonyl by the Lewis acidic siletane and intramolecular allylation. In this way, substrates containing multiple reactive carbonyl groups (e.g. ...[more]