Ontology highlight
ABSTRACT:
SUBMITTER: Modak D
PROVIDER: S-EPMC6769022 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Modak Debadrita D Sotomayor Marcos M
Communications biology 20190930
Cadherins form a large family of calcium-dependent adhesive proteins involved in morphogenesis, cell differentiation, and neuronal connectivity. Non-clustered δ1 protocadherins form a cadherin subgroup of proteins with seven extracellular cadherin (EC) repeats and cytoplasmic domains distinct from those of classical cadherins. Non-clustered δ1 protocadherins mediate homophilic adhesion and have been implicated in various diseases including asthma, autism, and cancer. Here we present X-ray crysta ...[more]