Ontology highlight
ABSTRACT:
SUBMITTER: Pedone E
PROVIDER: S-EPMC6775159 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Nature communications 20191002 1
Cellular systems have evolved numerous mechanisms to adapt to environmental stimuli, underpinned by dynamic patterns of gene expression. In addition to gene transcription regulation, modulation of protein levels, dynamics and localization are essential checkpoints governing cell functions. The introduction of inducible promoters has allowed gene expression control using orthogonal molecules, facilitating its rapid and reversible manipulation to study gene function. However, differing protein sta ...[more]