Ontology highlight
ABSTRACT:
SUBMITTER: Xu Y
PROVIDER: S-EPMC6789219 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Xu Yonghu Y Chen Kai K Cai Yuanxia Y Cheng Cheng C Zhang Zihan Z Xu Guofeng G
American journal of translational research 20190915 9
Outcome for children with high-risk neuroblastoma (NB) remains suboptimal. Recurrence and metastasis caused by chemo-resistance is an underlying mechanism contributing to the poor prognosis. Aberrant expression of Rad51 is implicated in both radio- and chemo-sensitivity in many human malignancies. However, its clinical significance and relationship with chemo-sensitivity in NB remain undefined. In this study, Rad51 expression was first evaluated in 70 surgically resected NB specimens by immunoch ...[more]