Ontology highlight
ABSTRACT:
SUBMITTER: Vanden-Hehir S
PROVIDER: S-EPMC6794644 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Biomacromolecules 20190829 10
Polymeric nanoparticles (NPs) are attractive candidates for the controlled and targeted delivery of therapeutics in vitro and in vivo. However, detailed understanding of the uptake, location, and ultimate cellular fate of the NPs is necessary to satisfy safety concerns, which is difficult because of the nanoscale size of these carriers. In this work, we show how small chemical labels can be appended to poly(lactic acid-<i>co</i>-glycolic acid) (PLGA) to synthesize NPs that can then be imaged by ...[more]