Circulating Apolipoprotein L1 is associated with insulin resistance-induced abnormal lipid metabolism.
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ABSTRACT:
SUBMITTER: Nishimura K
PROVIDER: S-EPMC6795879 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
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Circulating Apolipoprotein L1 is associated with insulin resistance-induced abnormal lipid metabolism.
Nishimura Kenji K Murakami Taichi T Sakurai Toshihiro T Miyoshi Masashi M Kurahashi Kiyoe K Kishi Seiji S Tamaki Masanori M Tominaga Tatsuya T Yoshida Sumiko S Nagai Kojiro K Abe Hideharu H Hui Shu-Ping SP Kotani Kazuhiko K Doi Toshio T
Scientific reports 20191016 1
Circulating ApolipoproteinL1 (ApoL1) is a component of pre-β-high-density lipoprotein (HDL), however little is known about the relationship of ApoL1 with cardiometabolic factors. Considering previous studies reporting the correlation of ApoL1 to triglyceride, we have hypothesized that ApoL1 associates with insulin-related metabolism. The current study examined their associations in 126 non-diabetic subjects and 36 patients with type 2 diabetes (T2DM). Non-diabetic subjects demonstrated triglycer ...[more]
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