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Standardized volumetric plaque quantification and characterization from coronary CT angiography: a head-to-head comparison with invasive intravascular ultrasound.


ABSTRACT: OBJECTIVES:We sought to evaluate the accuracy of standardized total plaque volume (TPV) measurement and low-density non-calcified plaque (LDNCP) assessment from coronary CT angiography (CTA) in comparison with intravascular ultrasound (IVUS). METHODS:We analyzed 118 plaques without extensive calcifications from 77 consecutive patients who underwent CTA prior to IVUS. CTA TPV was measured with semi-automated software comparing both scan-specific (automatically derived from scan) and fixed attenuation thresholds. From CTA, %LDNCP was calculated voxels below multiple LDNCP thresholds (30, 45, 60, 75, and 90 Hounsfield units [HU]) within the plaque. On IVUS, the lipid-rich component was identified by echo attenuation, and its size was measured using attenuation score (summed score ? analysis length) based on attenuation arc (1?=?

SUBMITTER: Matsumoto H 

PROVIDER: S-EPMC6824266 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature

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Standardized volumetric plaque quantification and characterization from coronary CT angiography: a head-to-head comparison with invasive intravascular ultrasound.

Matsumoto Hidenari H   Watanabe Satoshi S   Kyo Eisho E   Tsuji Takafumi T   Ando Yosuke Y   Otaki Yuka Y   Cadet Sebastien S   Gransar Heidi H   Berman Daniel S DS   Slomka Piotr P   Tamarappoo Balaji K BK   Dey Damini D  

European radiology 20190426 11


<h4>Objectives</h4>We sought to evaluate the accuracy of standardized total plaque volume (TPV) measurement and low-density non-calcified plaque (LDNCP) assessment from coronary CT angiography (CTA) in comparison with intravascular ultrasound (IVUS).<h4>Methods</h4>We analyzed 118 plaques without extensive calcifications from 77 consecutive patients who underwent CTA prior to IVUS. CTA TPV was measured with semi-automated software comparing both scan-specific (automatically derived from scan) an  ...[more]

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