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ABSTRACT:
SUBMITTER: Nazarieh M
PROVIDER: S-EPMC6833256 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Nazarieh Maryam M Rajula Hema Sekhar Reddy HSR Helms Volkhard V
BMC bioinformatics 20191106 1
<h4>Background</h4>Sets of differentially expressed genes often contain driver genes that induce disease processes. However, various methods for identifying differentially expressed genes yield quite different results. Thus, we investigated whether this affects the identification of key players in regulatory networks derived by downstream analysis from lists of differentially expressed genes.<h4>Results</h4>While the overlap between the sets of significant differentially expressed genes determin ...[more]