Mono-6-Deoxy-6-Aminopropylamino-?-Cyclodextrin on Ag-Embedded SiO2 Nanoparticle as a Selectively Capturing Ligand to Flavonoids.

ABSTRACT: It has been increasingly important to develop a highly sensitive and selective technique that is easy to handle in detecting levels of beneficial or hazardous analytes in trace quantity. In this study, mono-6-deoxy-6-aminopropylamino-?-cyclodextrin (pr-?-CD)-functionalized silver-assembled silica nanoparticles (SiO2@Ag@pr-?-CD) for flavonoid detection were successfully prepared. The presence of pr-?-CD on the surface of SiO2@Ag enhanced the selectivity in capturing quercetin and myricetin among other similar materials (naringenin and apigenin). In addition, SiO2@Ag@pr-?-CD was able to detect quercetin corresponding to a limit of detection (LOD) as low as 0.55 ppm. The relationship between the Raman intensity of SiO2@Ag@pr-?-CD and the logarithm of the Que concentration obeyed linearity in the range 3.4-33.8 ppm (R2 = 0.997). The results indicate that SiO2@Ag@pr-?-CD is a promising material for immediately analyzing samples that demand high sensitivity and selectivity of detection.

SUBMITTER: Hahm E 

PROVIDER: S-EPMC6835478 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature