Effect of maximal-intensity exercise on systemic nitro-oxidative stress in men and women.

ABSTRACT: OBJECTIVES:The aim of this study was to test the hypotheses: (1) there is a negative correlation between protein and lipid oxidative damage following maximal-intensity exercise, and oxygen uptake and work intensity (%VO2max) at the respiratory compensation point (RCP) in women and men; (2) nitro-oxidative stress following maximal-intensity exercise results from the intensification of anaerobic processes and muscle fibre micro-damage. METHODS:Study participants comprised 20 women (21.34±1.57 years) and 20 men (21.97±1.41 years) who performed a treadmill incremental test (IT); VO2max: 45.08?±?0.91 and 57.38?±?1.22?mL?kg-1?min-1 for women and men, respectively. The oxidized low-density lipoprotein (ox-LDL), 3-nitrotyrosine (3-NT) concentration and creatine kinase (CK) as well as lactate dehydrogenase (LDH) activity were measured in the blood serum, and total antioxidative capacity (TAC) and lactate concentration (Lac) were determined in blood plasma before and after IT. RESULTS:After the IT, increases in ox-LDL, 3-NT, CK, and LDH were seen in both groups (P?

SUBMITTER: Wiecek M 

PROVIDER: S-EPMC6837471 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature