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Association of pretransplant and posttransplant program ratings with candidate mortality after listing.


ABSTRACT: The Scientific Registry of Transplant Recipients (SRTR) is responsible for understandable reporting of program metrics, including transplant rate, waitlist mortality, and posttransplant outcomes. SRTR developed five-tier systems for each metric to improve accessibility for the public. We investigated the associations of the five-tier assignments at listing with all-cause candidate mortality after listing, for candidates listed July 12, 2011-June 16, 2014. Transplant rate evaluations with one additional tier were associated with lower mortality after listing in kidney (hazard ratio [HR], 0.93 0.950.97 ), liver (HR, 0.87 0.900.92 ), and heart (HR, 0.92 0.961.00 ) transplantation. For lung transplant patients, mortality after listing was highest at programs with above- and below-average transplant rates and lowest at programs with average transplant rates, suggesting that aggressive acceptance behavior may not always provide a survival benefit. Waitlist mortality evaluations with one additional tier were associated with lower mortality after listing in kidney (HR, 0.94 0.960.99 ) transplantation, and posttransplant graft survival evaluations with one additional tier were associated with lower mortality after listing in lung (HR, 0.90 0.940.98 ) transplantation. Transplant rate typically had the strongest association with mortality after listing, but the strength of associations differed by organ.

SUBMITTER: Wey A 

PROVIDER: S-EPMC6837730 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature

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Association of pretransplant and posttransplant program ratings with candidate mortality after listing.

Wey Andrew A   Gustafson Sally K SK   Salkowski Nicholas N   Kasiske Bertram L BL   Skeans Melissa M   Schaffhausen Cory R CR   Israni Ajay K AK   Snyder Jon J JJ  

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20180821 2


The Scientific Registry of Transplant Recipients (SRTR) is responsible for understandable reporting of program metrics, including transplant rate, waitlist mortality, and posttransplant outcomes. SRTR developed five-tier systems for each metric to improve accessibility for the public. We investigated the associations of the five-tier assignments at listing with all-cause candidate mortality after listing, for candidates listed July 12, 2011-June 16, 2014. Transplant rate evaluations with one add  ...[more]

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