Ontology highlight
ABSTRACT:
SUBMITTER: Ramisch A
PROVIDER: S-EPMC6839171 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Genome biology 20191108 1
We present the software Condition-specific Regulatory Units Prediction (CRUP) to infer from epigenetic marks a list of regulatory units consisting of dynamically changing enhancers with their target genes. The workflow consists of a novel pre-trained enhancer predictor that can be reliably applied across cell types and species, solely based on histone modification ChIP-seq data. Enhancers are subsequently assigned to different conditions and correlated with gene expression to derive regulatory u ...[more]