Dataset Information

Free-running 3D whole heart myocardial T₁ mapping with isotropic spatial resolution.

ABSTRACT:

Purpose

To develop a free-running (free-breathing, retrospective cardiac gating) 3D myocardial T₁ mapping with isotropic spatial resolution.

Methods

The free-running sequence is inversion recovery (IR)-prepared followed by continuous 3D golden angle radial data acquisition. 1D respiratory motion signal is extracted from the k-space center of all spokes and used to bin the k-space data into different respiratory states, enabling estimation and correction of 3D translational respiratory motion, whereas cardiac motion is recorded using electrocardiography and synchronized with data acquisition. 3D translational respiratory motion compensated T₁ maps at diastole and systole were generated with 1.5 mm isotropic spatial resolution with low-rank inversion and high-dimensionality patch-based undersampled reconstruction. The technique was validated against conventional methods in phantom and 9 healthy subjects.

Results

Phantom results demonstrated good agreement (R² = 0.99) of T₁ estimation with reference method. Homogeneous systolic and diastolic 3D T₁ maps were reconstructed from the proposed technique. Diastolic septal T₁ estimated with the proposed method (1140 ± 36 ms) was comparable to the saturation recovery single-shot acquisition (SASHA) sequence (1153 ± 49 ms), but was higher than the modified Look-Locker inversion recovery (MOLLI) sequence (1037 ± 33 ms). Precision of the proposed method (42 ± 8 ms) was comparable to MOLLI (41 ± 7 ms) and improved with respect to SASHA (87 ± 19 ms).

Conclusions

The proposed free-running whole heart T₁ mapping method allows for reconstruction of isotropic resolution 3D T₁ maps at different cardiac phases, serving as a promising tool for whole heart myocardial tissue characterization.

SUBMITTER: Qi H

PROVIDER: S-EPMC6851769 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Free-running 3D whole heart myocardial T<sub>1</sub> mapping with isotropic spatial resolution.

Qi Haikun H Jaubert Olivier O Bustin Aurelien A Cruz Gastao G Chen Huijun H Botnar René R Prieto Claudia C

Magnetic resonance in medicine 20190517 4

<h4>Purpose</h4>To develop a free-running (free-breathing, retrospective cardiac gating) 3D myocardial T<sub>1</sub> mapping with isotropic spatial resolution.<h4>Methods</h4>The free-running sequence is inversion recovery (IR)-prepared followed by continuous 3D golden angle radial data acquisition. 1D respiratory motion signal is extracted from the k-space center of all spokes and used to bin the k-space data into different respiratory states, enabling estimation and correction of 3D translatio ...[more]

PMID: 31099442

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Dataset Information

Free-running 3D whole heart myocardial T₁ mapping with isotropic spatial resolution.

Purpose

Methods

Results

Conclusions

Publications

Free-running 3D whole heart myocardial T<sub>1</sub> mapping with isotropic spatial resolution.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

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Dataset Information

Free-running 3D whole heart myocardial T1 mapping with isotropic spatial resolution.

Purpose

Methods

Results

Conclusions

Publications

Free-running 3D whole heart myocardial T<sub>1</sub> mapping with isotropic spatial resolution.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets

Free-running 3D whole heart myocardial T₁ mapping with isotropic spatial resolution.