Ontology highlight
ABSTRACT:
SUBMITTER: Jennings LK
PROVIDER: S-EPMC6864463 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Jennings Laurence K LK Khan Neyaz M D NMD Kaur Navdeep N Rodrigues Daniel D Morrow Christine C Boyd Aoife A Thomas Olivier P OP
Molecules (Basel, Switzerland) 20191029 21
As part of an ongoing program to identify new bioactive compounds from Irish marine bioresources, we selected the subtidal sponge <i>Spongosorites calcicola</i> for chemical study, as fractions of this species displayed interesting cytotoxic bioactivities and chemical profiles. The first chemical investigation of this marine species led to the discovery of two new bisindole alkaloids of the topsentin family, together with six other known indole alkaloids. Missing the usual central core featured ...[more]