Validation of the AJCC prognostic stage for HER2-positive breast cancer in the ShortHER trial.
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ABSTRACT:
SUBMITTER: Dieci MV
PROVIDER: S-EPMC6868696 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Publications
Validation of the AJCC prognostic stage for HER2-positive breast cancer in the ShortHER trial.
Dieci Maria Vittoria MV Bisagni Giancarlo G Brandes Alba A AA Frassoldati Antonio A Cavanna Luigi L Giotta Francesco F Aieta Michele M Gebbia Vittorio V Musolino Antonino A Garrone Ornella O Donadio Michela M Rimanti Anita A Beano Alessandra A Zamagni Claudio C Soto Parra Hector H Piacentini Federico F Danese Saverio S Ferro Antonella A Cagossi Katia K Sarti Samanta S Gambaro Anna Rita AR Romito Sante S Bazan Viviana V Amaducci Laura L Moretti Gabriella G Foschini Maria Pia MP Balduzzi Sara S Vicini Roberto R D'Amico Roberto R Griguolo Gaia G Guarneri Valentina V Conte Pier Franco PF
BMC medicine 20191121 1
<h4>Background</h4>The 8th edition of the American Joint Committee on Cancer (AJCC) staging has introduced prognostic stage based on anatomic stage combined with biologic factors. We aimed to validate the prognostic stage in HER2-positive breast cancer patients enrolled in the ShortHER trial.<h4>Methods</h4>The ShortHER trial randomized 1253 HER2-positive patients to 9 weeks or 1 year of adjuvant trastuzumab combined with chemotherapy. Patients were classified according to the anatomic and the p ...[more]
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