Ontology highlight
ABSTRACT:
SUBMITTER: Ruiz-Arenas C
PROVIDER: S-EPMC6873427 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Ruiz-Arenas Carlos C Cáceres Alejandro A Moreno Victor V González Juan R JR
Human genomics 20191121 1
<h4>Background</h4>Chromosomal inversions are structural genetic variants where a chromosome segment changes its orientation. While sporadic de novo inversions are known genetic risk factors for cancer susceptibility, it is unknown if common polymorphic inversions are also associated with the prognosis of common tumors, as they have been linked to other complex diseases. We studied the association of two well-characterized human inversions at 17q21.31 and 8p23.1 with the prognosis of lung, liver ...[more]