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Pleomorphic malignant fibrous histiocytoma in bladder diverticulum.


ABSTRACT: The Malignant Fibrous Histiocytoma is a very rare cancer and rather exceptional when located in bladder diverticulum. it occurs in men in their sixties, manifests itself through haematuria and/or irritative micturition. There is not a causal association. An immunohistochemical analysis is necessary to establish a differential diagnosis. It is aggressive, with a high rate of local recurrence and remote progression, thereby requiring early treatment that consists of radical cystectomy with pelvic lymph node dissection followed by adjuvant therapy, predominantly radiotherapy on the surgical wound. Close follow-up is crucially important. Poor survival rate even when patients undergo multimodal therapy.

SUBMITTER: Garcia Alvarez C 

PROVIDER: S-EPMC6879995 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

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Pleomorphic malignant fibrous histiocytoma in bladder diverticulum.

García Alvarez C C   González Alvarez R J RJ   Plata Bello A C AC   Alvarez-Argüelles Cabrera H H   Concepción Masip T T  

Urology case reports 20191118


The Malignant Fibrous Histiocytoma is a very rare cancer and rather exceptional when located in bladder diverticulum. it occurs in men in their sixties, manifests itself through haematuria and/or irritative micturition. There is not a causal association. An immunohistochemical analysis is necessary to establish a differential diagnosis. It is aggressive, with a high rate of local recurrence and remote progression, thereby requiring early treatment that consists of radical cystectomy with pelvic  ...[more]

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