Ontology highlight
ABSTRACT:
SUBMITTER: Whitman EJ
PROVIDER: S-EPMC6880746 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Whitman Eric J EJ Pomerantz Mark M Chen Yongmei Y Chamberlin Michael M MM Furusato Bungo B Gao Chunling C Ali Amina A Ravindranath Lakshmi L Dobi Albert A Sesterhenn Isabell A IA McLeod David G DG Srivastava Shiv S Freedman Matthew M Petrovics Gyorgy G
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20100101 1
<h4>Purpose</h4>A region on chromosome 8q24 was recently identified as a novel prostate cancer risk locus. Inherited variation in this region is associated with prostate cancer risk in the general population (21-58%), and specific alleles show a strong association in African-American men. This study was designed to evaluate associations between 8q24 risk alleles and clinical variables, such as pathologic stage, age at diagnosis, and recurrence, in a case series of African-American men.<h4>Experi ...[more]