Ontology highlight
ABSTRACT:
SUBMITTER: Korsunsky I
PROVIDER: S-EPMC6884693 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Nature methods 20191118 12
The emerging diversity of single-cell RNA-seq datasets allows for the full transcriptional characterization of cell types across a wide variety of biological and clinical conditions. However, it is challenging to analyze them together, particularly when datasets are assayed with different technologies, because biological and technical differences are interspersed. We present Harmony (https://github.com/immunogenomics/harmony), an algorithm that projects cells into a shared embedding in which cel ...[more]