Ontology highlight
ABSTRACT:
SUBMITTER: Moeller JB
PROVIDER: S-EPMC6888979 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Moeller Jesper B JB Leonardi Irina I Schlosser Anders A Flamar Anne-Laure AL Bessman Nicholas J NJ Putzel Gregory Garbès GG Thomsen Theresa T Hammond Mark M Jepsen Christine S CS Skjødt Karsten K Füchtbauer Ernst-Martin EM Farber Donna L DL Sorensen Grith L GL Iliev Iliyan D ID Holmskov Uffe U Artis David D Artis David D
The Journal of experimental medicine 20191010 12
Host-microbiota interactions are critical in regulating mammalian health and disease. In addition to bacteria, parasites, and viruses, beneficial communities of fungi (the mycobiome) are important modulators of immune- and tissue-homeostasis. Chitin is a major component of the fungal cell wall, and fibrinogen C containing domain 1 (FIBCD1) is a chitin-binding protein; however, the role of this molecule in influencing host-mycobiome interactions in vivo has never been examined. Here, we identify ...[more]