Ontology highlight
ABSTRACT:
SUBMITTER: Jiang T
PROVIDER: S-EPMC6891076 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Jiang Tao T Harris Tony J C TJC
The Journal of cell biology 20191022 12
Cell structure depends on the cortex, a thin network of actin polymers and additional proteins underlying the plasma membrane. The cell polarity kinase Par-1 is required for cells to form following syncytial <i>Drosophila</i> embryo development. This requirement stems from Par-1 promoting cortical actin caps that grow into dome-like metaphase compartments for dividing syncytial nuclei. We find the actin caps to be a composite material of Diaphanous (Dia)-based actin bundles interspersed with ind ...[more]