Ontology highlight
ABSTRACT:
SUBMITTER: Liu W
PROVIDER: S-EPMC6896371 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Oncology letters 20191101 6
Lung cancer, especially non-small cell lung cancer (NSCLC), is the most common malignant tumor associated with poor prognosis. Angiogenesis plays a vital role in NSCLC, and could be used in tumor staging and therapy evaluation. CD93 (C1q receptor) is reportedly a key regulator of tumor angiogenesis. In the present study, the efficacy and specificity of a <sup>125</sup>I-labeled CD93-specific monoclonal antibody (<sup>125</sup>I-anti-CD93 mAb) in detecting NSCLC xenografts were analyzed, and the ...[more]