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Recalcitrant Issues and New Frontiers in Nano-Pharmacology.


ABSTRACT: Packaging of old pharma drugs into new packaging "nanoparticles" is called nano-pharmacology and the products are called nano-based drugs. The inception of nano-pharmacology research and development (R&D) is marked by the approval of the first nano-based drug Doxil® in 1995 by the Food and Drug Administration. However, even after more than two decades, today, there are only ?20 nano-based drugs in the market to treat cancers and brain diseases. In this article we share the perspectives of nanotechnology scientists, engineers, and clinicians on the roadblocks in nano-pharmacology R&D. Also, we share our opinion on new frontiers in the field of nano-pharmacology R&D that may allow rapid and efficient transfer of nano-pharma technologies from R&D to market.

SUBMITTER: Bhardwaj V 

PROVIDER: S-EPMC6897283 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Recalcitrant Issues and New Frontiers in Nano-Pharmacology.

Bhardwaj Vinay V   Kaushik Ajeet A   Khatib Ziad M ZM   Nair Madhavan M   McGoron Anthony J AJ  

Frontiers in pharmacology 20191129


Packaging of old pharma drugs into new packaging "nanoparticles" is called nano-pharmacology and the products are called nano-based drugs. The inception of nano-pharmacology research and development (R&D) is marked by the approval of the first nano-based drug Doxil<sup>®</sup> in 1995 by the Food and Drug Administration. However, even after more than two decades, today, there are only ∼20 nano-based drugs in the market to treat cancers and brain diseases. In this article we share the perspective  ...[more]

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