Ontology highlight
ABSTRACT:
SUBMITTER: Thomsen RP
PROVIDER: S-EPMC6906287 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Nature communications 20191211 1
Transmembrane nanostructures like ion channels and transporters perform key biological functions by controlling flow of molecules across lipid bilayers. Much work has gone into engineering artificial nanopores and applications in selective gating of molecules, label-free detection/sensing of biomolecules and DNA sequencing have shown promise. Here, we use DNA origami to create a synthetic 9 nm wide DNA nanopore, controlled by programmable, lipidated flaps and equipped with a size-selective gatin ...[more]