Ontology highlight
ABSTRACT:
SUBMITTER: Mejzini R
PROVIDER: S-EPMC6909825 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Mejzini Rita R Flynn Loren L LL Pitout Ianthe L IL Fletcher Sue S Wilton Steve D SD Akkari P Anthony PA
Frontiers in neuroscience 20191206
The scientific landscape surrounding amyotrophic lateral sclerosis (ALS) continues to shift as the number of genes associated with the disease risk and pathogenesis, and the cellular processes involved, continues to grow. Despite decades of intense research and over 50 potentially causative or disease-modifying genes identified, etiology remains unexplained and treatment options remain limited for the majority of ALS patients. Various factors have contributed to the slow progress in understandin ...[more]