Engineering a Bi-Conical Microchip as Vascular Stenosis Model.
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ABSTRACT:
SUBMITTER: Li Y
PROVIDER: S-EPMC6915513 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Publications
Engineering a Bi-Conical Microchip as Vascular Stenosis Model.
Li Yan Y Wang Jianchun J Wan Wei W Chen Chengmin C Wang Xueying X Zhao Pei P Hou Yanjin Y Tian Hanmei H Wang Jianmei J Nandakumar Krishnaswamy K Wang Liqiu L
Micromachines 20191118 11
Vascular stenosis is always associated with hemodynamic changes, especially shear stress alterations. Herein, bi-conical shaped microvessels were developed through flexibly and precisely controlled templated methods for hydrogel blood-vessel-like microchip. The blood-vessel-like microvessels demonstrated tunable dimensions, perfusable ability, and good cytocompatibility. The microchips showed blood-vessel-like lumens through fine embeddedness of human umbilical vein endothelial cells (HUVECs) on ...[more]
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