Ontology highlight
ABSTRACT:
SUBMITTER: Pagan-Diaz GJ
PROVIDER: S-EPMC6926042 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Pagan-Diaz Gelson J GJ Ramos-Cruz Karla P KP Sam Richard R Kandel Mikhail E ME Aydin Onur O Saif M Taher A MTA Popescu Gabriel G Bashir Rashid R
Proceedings of the National Academy of Sciences of the United States of America 20191203 51
Formation of tissue models in 3 dimensions is more effective in recapitulating structure and function compared to their 2-dimensional (2D) counterparts. Formation of 3D engineered tissue to control shape and size can have important implications in biomedical research and in engineering applications such as biological soft robotics. While neural spheroids routinely are created during differentiation processes, further geometric control of in vitro neural models has not been demonstrated. Here, we ...[more]