Ontology highlight
ABSTRACT:
SUBMITTER: Li Q
PROVIDER: S-EPMC4715930 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Li Qiyao Q Chang Zhen Z Oliveira Gisele G Xiong Maiyer M Smith Lloyd M LM Frey Brian L BL Welham Nathan V NV
Biomaterials 20151214
Repopulating acellular biological scaffolds with phenotypically appropriate cells is a promising approach for regenerating functional tissues and organs. Under this tissue engineering paradigm, reseeded cells are expected to remodel the scaffold by active protein synthesis and degradation; however, the rate and extent of this remodeling remain largely unknown. Here, we present a technique to measure dynamic proteome changes during in vitro remodeling of decellularized tissue by reseeded cells, u ...[more]