Ontology highlight
ABSTRACT:
SUBMITTER: Schifano E
PROVIDER: S-EPMC6930020 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Schifano Emily E Ficociello Graziella G Vespa Simone S Ghosh Salil S Cipollo John F JF Talora Claudio C Lotti Lavinia Vittoria LV Mancini Patrizia P Uccelletti Daniela D
Virulence 20191201 1
Calcium signaling can elicit different pathways involved in an extreme variety of biological processes. Calcium levels must be tightly regulated in a spatial and temporal manner in order to be efficiently and properly utilized in the host physiology. The Ca<sup>2+</sup>-ATPase, encoded by <i>pmr-1</i> gene, was first identified in yeast and localized to the Golgi and it appears to be involved in calcium homeostasis. PMR-1 function is evolutionary conserved from yeast to human, where mutations in ...[more]