Ontology highlight
ABSTRACT:
SUBMITTER: Pendergrass SA
PROVIDER: S-EPMC6938343 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Pendergrass Sarah A SA Buyske Steven S Jeff Janina M JM Frase Alex A Dudek Scott S Bradford Yuki Y Ambite Jose-Luis JL Avery Christy L CL Buzkova Petra P Deelman Ewa E Fesinmeyer Megan D MD Haiman Christopher C Heiss Gerardo G Hindorff Lucia A LA Hsu Chun-Nan CN Jackson Rebecca D RD Lin Yi Y Le Marchand Loic L Matise Tara C TC Monroe Kristine R KR Moreland Larry L North Kari E KE Park Sungshim L SL Reiner Alex A Wallace Robert R Wilkens Lynne R LR Kooperberg Charles C Ritchie Marylyn D MD Crawford Dana C DC
PloS one 20191231 12
We performed a hypothesis-generating phenome-wide association study (PheWAS) to identify and characterize cross-phenotype associations, where one SNP is associated with two or more phenotypes, between thousands of genetic variants assayed on the Metabochip and hundreds of phenotypes in 5,897 African Americans as part of the Population Architecture using Genomics and Epidemiology (PAGE) I study. The PAGE I study was a National Human Genome Research Institute-funded collaboration of four study sit ...[more]