Ontology highlight
ABSTRACT:
SUBMITTER: Ghanim GE
PROVIDER: S-EPMC6948148 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Ghanim George E GE Kellogg Elizabeth H EH Nogales Eva E Rio Donald C DC
Nature structural & molecular biology 20191028 11
P element transposase catalyzes the mobility of P element DNA transposons within the Drosophila genome. P element transposase exhibits several unique properties, including the requirement for a guanosine triphosphate cofactor and the generation of long staggered DNA breaks during transposition. To gain insights into these features, we determined the atomic structure of the Drosophila P element transposase strand transfer complex using cryo-EM. The structure of this post-transposition nucleoprote ...[more]