Ontology highlight
ABSTRACT:
SUBMITTER: Yang Y
PROVIDER: S-EPMC6949103 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Yang Yong Y Yuan Guangda G Xie Hongya H Wei Tengteng T Zhu Donglin D Cui Jianyong J Liu Xiaoqiang X Shen Rongming R Zhu Yimeng Y Yang Xuefang X
Aging 20191223 24
The application of cancer chronotherapy is to treat cancers based on at specific times during circadian rhythms. Previous studies have characterized the impact of circadian clock on tumorigenesis and specific immune cells. Here, by using multi-omics computation techniques, we systematically characterized the distinct roles of core circadian clock genes in thoracic cancers including lung adenocarcinoma, lung squamous cell carcinoma, and esophageal carcinoma. Strikingly, a wide range of core clock ...[more]