Syntaxin 16's Newly Deciphered Roles in Autophagy.
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ABSTRACT:
SUBMITTER: Tang BL
PROVIDER: S-EPMC6953085 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Publications
Syntaxin 16, a Qa-SNARE (soluble <i>N</i>-ethylmaleimide-sensitive factor activating protein receptor), is involved in a number of membrane-trafficking activities, particularly transport processes at the trans-Golgi network (TGN). Recent works have now implicated syntaxin 16 in the autophagy process. In fact, syntaxin 16 appears to have dual roles, firstly in facilitating the transport of ATG9a-containing vesicles to growing autophagosomes, and secondly in autolysosome formation. The former invo ...[more]
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