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PennPET Explorer: Design and Preliminary Performance of a Whole-Body Imager.

ABSTRACT: We report on the development of the PennPET Explorer whole-body imager. Methods: The PennPET Explorer is a multiring system designed with a long axial field of view. The imager is scalable and comprises multiple 22.9-cm-long ring segments, each with 18 detector modules based on a commercial digital silicon photomultiplier. A prototype 3-segment imager has been completed and tested with an active 64-cm axial field of view. Results: The instrument design is described, and its physical performance measurements are presented. These include sensitivity of 55 kcps/MBq, spatial resolution of 4.0 mm, energy resolution of 12%, timing resolution of 256 ps, and a noise-equivalent count rate above 1,000 kcps beyond 30 kBq/mL. After an evaluation of lesion torso phantoms to characterize quantitative accuracy, human studies were performed on healthy volunteers. Conclusion: The physical performance measurements validated the system design and led to high-quality human studies.

SUBMITTER: Karp JS

PROVIDER: S-EPMC6954465 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

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PennPET Explorer: Design and Preliminary Performance of a Whole-Body Imager.

Karp Joel S JS Viswanath Varsha V Geagan Michael J MJ Muehllehner Gerd G Pantel Austin R AR Parma Michael J MJ Perkins Amy E AE Schmall Jeffrey P JP Werner Matthew E ME Daube-Witherspoon Margaret E ME

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20190621 1

We report on the development of the PennPET Explorer whole-body imager. <b>Methods:</b> The PennPET Explorer is a multiring system designed with a long axial field of view. The imager is scalable and comprises multiple 22.9-cm-long ring segments, each with 18 detector modules based on a commercial digital silicon photomultiplier. A prototype 3-segment imager has been completed and tested with an active 64-cm axial field of view. <b>Results:</b> The instrument design is described, and its physica ...[more]

PMID: 31227573

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Dataset Information

PennPET Explorer: Design and Preliminary Performance of a Whole-Body Imager.

Publications

PennPET Explorer: Design and Preliminary Performance of a Whole-Body Imager.

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