Unknown

Dataset Information

0

Next-Generation Whole-Cell Pneumococcal Vaccine.


ABSTRACT: Streptococcus pneumoniae remains a major public health hazard. Although Pneumococcal Conjugate Vaccines (PCVs) are available and have significantly reduced the rate of invasive pneumococcal diseases, there is still a need for new vaccines with unlimited serotype coverage, long-lasting protection, and lower cost to be developed. One of the most promising candidates is the Whole-Cell Pneumococcal Vaccine (WCV). The new generation of whole-cell vaccines is based on an unencapsulated serotype that allows the expression of many bacterial antigens at a lower cost than a recombinant vaccine. These vaccines have been extensively studied, are currently in human trial phase 1/2, and seem to be the best treatment choice for pneumococcal diseases, especially for developing countries.

SUBMITTER: Morais V 

PROVIDER: S-EPMC6963273 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC4514174 | biostudies-literature
| PRJEB24733 | ENA
| S-EPMC4773897 | biostudies-literature
| S-EPMC3216348 | biostudies-literature
| S-EPMC3861478 | biostudies-other
| S-EPMC3692352 | biostudies-literature
| S-EPMC10805787 | biostudies-literature
| S-EPMC4313294 | biostudies-literature
| S-EPMC7773144 | biostudies-literature
| S-EPMC3599116 | biostudies-literature